Improving the Antigenicity of SARS-CoV-2 Vaccine Genes by Merging Mutations from Different Variants of Concern
During the COVID-19 pandemic, the early emergence of viral variants repeatedly undermined the effects of vaccination.Our aim here is to explore strategies for improving spike vaccine gene antigenicity by merging mutations from different variants of concern (VOCs) in a single vaccine gene.To this end, newly developed recombinant texas bag ego vaccin